Generic Stendra (Avanafil) vs. Kamagra (Sildenafil): Understanding Differences and Common Features


Modern pharmaceutical market is abundant of various ED treatment drugs. Why are they so popular and what are the reasons of their number growth? The answer is quite evident. The modern world has faced the growing problem of men’s sexual dysfunctions. The factors influencing the situation involve bad habits, sedentary lifestyle, stresses and bad environment. Thus, ED treatment drugs’ popularity forces pharmaceutical producers to offer new products in order to meet the requirements of the market. This article is dedicated to Kamagra that is already well – known at the market and Stendra, a relatively new medication that appeared several years ago.Stendra vs. Kamagra Understanding Differences and Common Features

What is common about Stendra and Kamagra?

The major common feature of Stendra and Kamagra is their reference to the group of PDE5 inhibitors which main indication is a treatment of the erectile dysfunction. Having appeared nearly 20 years ago these medications provided a lot of men all over the world with the chance to improve their sexual life without considerable interventions into their body (we mean various kinds of surgical intervention).

PDE5 inhibitors are characterized by high efficiency, relatively small quantity of side effects (though pharmaceutical companies try to warn even about the rarest ones) and good acceptability.

Avanafil vs. Sildenafil

The medications have different active ingredients: Sildenafil – for Kamagra and Avanafil – for Stendra. Sildenafil is considered to be a pioneer of PDE5 inhibitors as it was the first substance that was tested and recognized to have ED treatment properties in 1998. Sildenafil is used in Viagra, the legend of the pharmaceutical industry. By the way, it is the reason why Kamagra is often called a generic (or affordable) Viagra.

Avanafil refers to the group of new-generation medications; it was invented in 2011 and approved by FDA in 2012. Avanafil is known for its fast absorption and response. The large quantity of clients notes the ability to start sexual intercourse in 15 minutes after the intake of Stendra. The therapeutic action of Stendra usually lasts 6 hours.

At the same time Kamagra’s action starts in 40-60 minutes after the intake of the pill and lasts 4 hours.

How to take and What to avoid?

How to take and What to avoid

PDE5 inhibitors are taken once a day before the planned sexual intercourse. In case of Stendra it takes 15 – 30 minutes for the medication to start acting. If the patient takes Kamagra he may need 40 to 60 minutes before the coitus as Kamagra requires more time to start.

While choosing between these two drugs one should remember that in case of Sildenafil (Kamagra) the starting dosage should be 50 mg or even 25 mg (especially when it concerns elderly patients). The largest recommended dosage of Sildenafil is 100 mg.

The starting dose of Avanafil is 100 mg (patients over 65 should start with 50 mg). If everything is OK for the patient’s health, he can try 200 mg of Avanafil.

When it comes to contraindications and side effects Stendra and Kamagra have nearly no differences. Both Stendra and Kamagra are not prescribed together with nitroglycerin and other nitrate containing drugs. As for the other medications Stendra and Kamagra should be prescribed with the medications are prescribed with care if the patient has already been taking antibiotics, antifungal drugs and some antidepressants. So, don’t forget to consult your doctor before you start the therapy.

People with cardio vascular problems are not recommended taking Sildenafil or Avanafil. The given recommendation also refers to those patients who suffer from gastrointestinal diseases, some mental disorders and others.

The most common side effects of Kamagra and Stendra include headaches, hot flushes and dizziness.

Available forms and dosages

Being very popular Kamagra is available in various pharmaceutical forms. A patient may choose standard coated pill of Kamagra, Kamagra Chewable or Oral Jelly if he has problems with swallowing. Moreover, Kamagra is manufactured in the soluble form (Kamatra Effervescent that is completely dissolved in water) and is available in the combination with Dapoxetine, the medication applied for the treatment of the premature ejaculation (Kamagra Super).

Both standard and special forms of Kamagra contain 50 or 100 mg of Sildenafil and are available in various package sizes (from 10 to 270 pills per pack). The effectiveness of Kamagra is the same regardless of the pharmaceutical form.

Unlike Kamagra Stendra is produced only in one form that is a coated pill. The Avanafil content is offered in two dosages: 50 and 100 mg. Package size differs from 10 to 270 pills per pack.

Stendra and Kamagra are widely available in online pharmaceutical services like Canadian Pharmacy where people can find various pharmaceutical products at very attractive prices.

Stendra vs. Kamagra: Effectiveness and Customer’s Feedbacks

Kamagra has already become popular with patients because of its effectiveness, affordable price and relatively rare cases of side effects. Surely, certain quantity patients taking Kamagra suffer from undesired consequences especially at the very beginning (that is typical of Sildenafil) however, some of them even agree to overcome pain in order to have the effect. There are some negative feedbacks as no medication has 100% positive effect on all patients. Nevertheless, negative feedbacks about Kamagra is quite rare.

As far as Stendra is concerned the number of positive and negative feedbacks is nearly equal. We do not know what the reasons of such situation are, but Internet forums and feedbacks are divided into two groups: very positive and very negative. Some people consider Stendra to be one of the most effective ED treatment drugs and the other declare that it does not work for them at all. However, all of them underline that the price for Stendra is very attractive.

To sum it up

Kamagra and Stendra are effective and safe ED treatment drugs. They are widely available via online pharmaceutical services and are popular with patients.

They are characterized by similar side effects and contraindications; however have certain differences in pharmaceutical forms, time of intake and medical action. Both Stendra and Kamagra require additional medical consultation and health monitoring during the therapy.

Canadian Pharmacy summary of Kamagra uses, effects, cautions and tips

Kamagra helps men affected by ED to achieve and maintain an erection. Sildenafil is used to treat erectile dysfunction and to reduce erectile dysfunction and increase erectile function. The active ingredient has no anti-stress effect, that is, it does not automatically lead to an erection after an intake.

Canadian Pharmacy summary of Kamagra uses, effects, cautions and tips

The active substance sildenafil is added to the group of phosphodiesterase inhibitors. For the production of an erection, nitrogen (NO) activates the release of the messenger cGMP (cyclic guanine monophosphate), which causes the smooth muscle to relax in the penis. Thus the blood can flow into the corpus cavernosum.

The enzyme PDE5, on the other hand, is formed when the sexual climax is reached and the erection should be relieved. In the case of impotence, this enzyme is released too early so that it either leads to an early decay of the erection or does not result in an erection. The active substance sildenafil contained in Kamagra is involved in this process and inhibits the enzyme PDE5. Thus, the release of the enzyme is delayed and the messenger cGMP remains active for longer.

Kamagra is taken 30 to 60 minutes before sexual intercourse. Do not take Kamagra if you are pregnant or breast-feeding. The film tablets are swallowed whole with a little water. The effect of Kamagra is 4 to 5 hours, during which time the sexual act can be performed several times.

Kamagra film tablets should be taken 30 minutes before the scheduled sexual act. The recommended initial dose is 50 mg unless the doctor has prescribed a different dosage. Depending on the efficacy or tolerability, the dose can be reduced to 25 mg or increased to 100 mg. The recommended maximum dose is 100 mg per day. Do not take more than once a day. In men over 65 years of age no dose adjustment is required. The drug is not indicated for use in children and adolescents under 18 years of age.

The enjoyment of alcohol can degrade the ability to achieve an erection. To get the most benefit from Kamagra, do not drink large amounts of alcohol before taking the medication. If Kamagra is taken with greasy food, the effect of the drug may be delayed compared to sober intake.

If Kamagra is taken, this should not be done with grapefruit juice. The substance furanocoumarins, which is contained in grapefruit, blocks the enzyme CYP3A4, which causes the degradation of substances in the intestine. As a result, the concentration of sildenafil in the blood increases and the risk of side effects are increased.

Most side effects known to occur with Kamagra are usually mild to moderate and of short duration. If chest pain is experienced during or after sexual intercourse, it is recommended that you take a half-biting posture and relax. No nitrates should be used and the doctor should be immediately and immediately notified.

All medicines, including Kamagra, can cause an allergic reaction. A doctor should be immediately informed if the following symptoms are noticed after taking Kamagra: swelling of the eyelid, face, lips, or throat, difficulty breathing or dizziness, sudden startling whistling.

The following symptoms should also be immediately consulted by a physician: if a sudden deterioration or loss of vision is observed, or an excessively long-lasting, sometimes even painful, erection of more than four hours is present. Taking Kamagra can affect your vision and cause dizziness. Individual attention should be paid to how the personal response to the drug is presented before a vehicle is steered or machines operated.

The active substance sildenafil and some drugs may interfere with each other and thus cause interactions. This applies in particular to medicines used for the treatment of heart disease.

As a general rule, Kamagra should not be used with medicines containing the following active ingredients:

  • (For the treatment of angina pectoris) Isosorbide mononitrate (used to treat angina pectoris) Isosorbide dinitrate (used to treat angina pectoris / coronary sclerosis)
  • Sildenafil should also not be used if concurrent medications for pulmonary arterial hypertension, enlarged prostate, HIV or hepatitis C are taken. In addition, nitrate-containing drugs (for the treatment of heart diseases) can cause an acute blood pressure drop.

In case of hypersensitivity to the active substance or to any of the other ingredients in the tablet, Kamagra should not be taken. Since sildenafil enhances the blood pressure lowering effect of nitrates, co-administration with nitric oxide donors and any nitrates is contraindicated.

People with severe cardiovascular disease such as unstable angina or severe heart failure, cannot take Kamagra. Your physician or any other prescriber will inform you about other counter-indications in which sildenafil is contraindicated. Alternatively, these can be found in the detailed package leaflet. The medicine should not be taken under any circumstances if the doctor does not specifically allow it.

Dosage recommendations for adult men also apply to men with mild to moderate renal insufficiency. In men with hepatic impairment, as a rule, a dose of 25 mg can be considered. Depending on the efficacy and tolerability of Kamagra, the dose may be increased step by step to 50 mg to 100 mg if necessary.

If you experience any side effects while you are taking Kamagra, tell your doctor or pharmacist as soon as possible. If a side effect suddenly develops or develops strongly, the medication should not be taken further without a doctor’s prescription until re-diagnosis.

Kamagra and Stendra vs. Stendra in answers and questions by My Canadian Pharmacy Rx

  1. What kind of drugs are Kamagra and Stendra?

Kamagra and Stendra are medications for the treatment of impotence (erectile dysfunction / erectile dysfunction), which belong to the group of PDE5 inhibitors. The active ingredient sildenafil in Kamagra was first investigated for the treatment of hereditary diseases, but the potentiating side effects were found by chance. Sildenafil was therefore the first potency drug on the market and is therefore the most famous product used for this purpose. Avanafil had not appeared on the international pharmacological scene until 2013, when it became a fast favorite and a tough competitor for sildenafil.

  1. How do Kamagra and Stendra work?

The active ingredients sildenafil in Kamagra and avanafil in Stendra inhibit the enzyme PDE5, which is normally released from the body to decay the body. If ED is present, this enzyme is produced too early and there can be no erection or the erection sounds too early.

  1. How fast do Kamagra and Stendra work and how long do they last?

The effect occurs between 30 minutes and 1 hour after ingestion. If the tablet is taken with a fat-rich diet, this may delay the effect of the action. The onset of avanafil effects occurs within 15-30 minutes after the intake, reaching its peak after 60 minutes. The effects of both Kamagra and Stendra last during 4-5 hours. During this time the sexual act can be performed several times.

  1. What dosage of sildenafil and avanafil is optimal?

Sildenafil is available in 3 doses, 50mg is the recommended starting dose. If severe side effects occur with this administration or the effect is not sufficient, the dosage can be adapted to 25 mg or 100 mg. Avanafil comes in dosages 50, 100 and 200mg, with the recommended initial dose of 50mg.

  1. How re Kamagra and Stendra taken?

Kamagra and Stendra are taken 15-60 minutes before the scheduled sexual act, taken with a glass of water. No alcohol should be taken at the same time or grapefruit or grapefruit juice as this increases the concentration of the active substance sildenafil in the blood and the occurrence of side effects is more likely.

  1. What side effects are expected with Kamagra and Stendra?

Headaches, a stuffy nose and flush (reddened upper body) are the most common side effects. Sildenafil also causes a drop in blood pressure and can lead to dizziness. Further side effects can be found in the package leaflet.

  1. Can Kamagra and Stendra be taken despite hypertension?

Kamagra and Stendra should be taken without prescription in case of hypertension. Even if the person concerned takes medicines for the treatment of hypertension, the simultaneous use is safe. PDE5 inhibitors even lower the blood pressure even in the short term. However, alpha blockers, e.g. Doxazosin, Terazosin and Urapidil. Concomitant use with Kamagra and Stendra may lead to side effects such as dizziness.

  1. Can Kamagra and Stendra be taken despite heart disease?

If there are no counter-advertisements, e.g. the intake of nitrates, and can the patient basically deal with the physical stress of sex, Kamagra and Stendra can be in principle taken. To avoid unwanted side effects, a doctor should be consulted before taking the potency.

  1. Can Kamagra and Stendra be taken interchangeably?

In principle, they can. However, you will soon figure out which drug works best for you. This all depends on the individual response from your body, severity of your ED, existing comorbidities and a large number of other factors. Caution should be taken not to take both drugs simultaneously or on the same day. Allow at least 24 hours to pass between the intake of the same drug or the drugs of the same class. Roughly speaking, sildenafil and avanafil are two chemicals that are considered incompatible for concomitant use.

My Canadian Pharmacy Rx Stendra sum-up

My Canadian Pharmacy Rx Stendra sum-upIn the treatment of erectile dysfunction, a large number of affected patients use prescription medications such as Stendra and regain a stable sexual life without any performance pressure. The active ingredient avanafil contributes to the expansion of the blood vessels and supports the penis erection. The potency is already 15 to 30 minutes after intake and up to 6 hours. Therefore, Stendra supports a ‘spontaneous’ and multiple sexual intercourses.

The effect of Stendra is based on the PDE5 inhibitor avanafil. PDE5 stands for the enzyme phosphodiesterase5. The PDE5 occurs, among other things, in the penis of the penis and provides for the degradation of cyclic guanosine monophosphate (cGMP).

As with other medicines, it can lead to side effects when taking Stendra. The possible side effects of Stendra are divided into severe and other side effects. If severe side effects are observed, the treatment should be discontinued immediately and a doctor should be consulted.

Continuous (priapism) over 4 hours is one of the most serious side effects one can expect from Stendra. If a priapism is not treated in time, a permanent damage to the penis and a permanent loss of the erectile capacity is threatened. Priapism can be favored, for example, by sickle cell anemia, leukemia or a multiple myeloma. Blurred vision or sudden loss or sudden loss of vision. These symptoms can occur, for example, in a non-arteritic ischemic optic neuropathy (short: NAION). Sudden decrease or loss of hearing can occur while using Stendra. Symptoms may also be associated with dizziness or ringing in the ear.

Stendra may not be taken with other medicines, in case of an allergy to avanafil. the use of other medicines for erectile dysfunction. These include, for example, Viagra, Kamagra, Cialis or Levitra with the active ingredients sildenafil, tadalafil and vardenafil. the use of medicines against fungal infections such as ketoconazole, itraconazole or voriconazole. a treatment with antibiotics such as clarithromycin or telithromycin. the use of drugs against AIDS and HIV (for example ritonavir, indinavir, saquinavir, nelfinavir or atazanavir). a present angina pectoris, as well as other heart diseases or heart problems. existing or in the course of sexual intercourse. low (under 90/50 mmHg) or high blood pressure (higher 170/100 mmHg), which is not regulated by medication. severe liver and kidney disorders. a loss of vision due to an insufficient blood supply in the eye or severe eye problems in the kinship. Blood clotting disorders or acute peptic ulcers. Stroke or heart attacks that have occurred in the last 6 months. (priapism), or diseases that can cause a change in the shape of the penis. These include, but are not limited to, angulation, Peyronie disease, or coronary artery fibrosis, individuals under 18 years of age.

After taking Stendra, dizziness and reduced vision may occur. If these symptoms occur, driving and operating machinery must be omitted. It is therefore advisable to schedule at least the acquisition of Stendra in such a way that no car rides or the operation of machines must be carried out until the drug has been completely removed.