Tadalafil Drugs Compared: Cialis Vs. Adcirca

Tadalafil: So Much More Than ‘The Weekend Pill’

My Canadian Pharmacy Rx receives heaps of emails from customers with requests to review a new or long-existing drug, which we always do with pleasure. We actually encourage such inquisitiveness in our readers, since increased awareness about conditions, prevention and available treatments makes us health-savvy and more mindful in our choices. A quick note though: before you request a review, do check out the respective section of our website: chances are that we’ve already got the drug you need covered.

TadalafilIn case with tadalafil (generic name for Cialis and Tadacip), things are not as straight-forward though. True it is that we’ve been revisiting the topic of oral ED treatments, and PDE5 inhibitors class in particular, many a time. But it seems that the more attention we devote to those bad boys, the more versatile they become. The instances of off-label use of tadalafil and other inhibitors of phosphodiesterase type 5 may be anecdotal rather than systematic, but new drugs based on these substances spring into being with consistent regularity, and their applications are but a far cry, if at all connected to, their effects on the erectile function in men.

The capacity to do greater good is inherently immanent to tadalafil. The substance, legitimately celebrated for its heavy-duty longevity, is in this time and age of pharmacological science used for many other beneficial purposes. Benign prostate hyperplasia (BPH), pulmonary arterial hypertension (PAH), diabetes, high blood pressure – just to name a few. A curious historical footnote on PDE5 inhibitors is that the very first one of them, sildenafil citrate, the bellwether of the class which we all now know as the freakishly famous Viagra, was the result of research work aimed at finding a PAH medicine.

The substance tadalafil branded as Cialis burst on the scene some five years later, boasting a whole new level of longevity. This goes to show just how essentially multitasking the substance can be when put to some right use, inspiring one scientific breakthrough right after another. So stay with us to learn more productive facts about the world’s favorite ‘Weekend Pill’, as it is lovingly monikered by doctors and patients. In the article below we will try to bring you along with us on two other basic use of tadalafil than the one you are only too familiar with right now, ED treatment.

The Common Denominator: Tadalafil In Cialis And Adcirca

AdcircaWhile the brand name of Cialis seems to be on everybody’s lips in the industry and among rank and file consumers, if we were to drop the name of Adcirca it would hardly ring a bell. ­This is because until fairly recently, tadalafil had only received large-scale manufacturing as an ED drug called Cialis (commercialized Tadacip when produced by a generic manufacturer based in India).

Adcirca is a tadalafil preparation that is indicated for the use in adult population suffering from the aforementioned conditions of BPH and PAH. It allows to address issues with exercise capacity that manifest themselves symptomatically in individuals ailed by PAH which is linked to Ehlers-Danlos syndrome (EDS).

Ehlers-Danlos syndrome (EDS, or collagen vascular disease) is a congenital connective tissue defect that affects the joints, skin and blood vessels. Changes in the connective tissue happen due to defective collagen, one of the body’s basic building materials and the most common protein in humans. Collagen represents nearly a third of the total body protein content. There are combinations of at least 25 different collagen in skin, bone, tendons, cartilage, blood vessels, gums, basement membranes, cornea, vitreous of the eye and supporting tissues in the internal organs. Collagen chains bind together in threes to form threads (fibrils) with great strength. In Ehlers-Danlos Syndrome fibrils have a sparser and altered structure that allows the strength of the tissues become weaker. It provides increased joint mobility, overstretched and / or soft skin and sometimes fragile vessel walls. Other proteins with similar functions is becoming known, and in some cases of Ehlers-Danlos Syndrome have found changes in any of these proteins.

Adcirca is successfully implemented as a means to treat benign prostatic hyperplasia (also called BPH), which is non-cancerous (ie not linked to tumors) enlargement of the prostate gland, exclusively male organ. BPH is also more commonly called benign prostatic hypertrophy or, sometimes, benign prostatic obstruction.

The prostate has two main periods of growth during the life of a man:

  • The first occurs early in puberty, when the prostate doubles in size;
  • The second period begins at age 25 and continues throughout most of his life.
  • This condition often occurs during the second phase of growth.

Gradually the gland enlarges, it compresses and crushes the urethra. The bladder walls tend to thicken. Over time, the bladder can weaken, lose the ability to empty itself completely and then hold a little ‘residual urine. The narrowing of the urethra and urinary retention (the failure to complete emptying of the bladder) cause many of the problems associated with benign prostatic hyperplasia.

There is a number of criteria to meet in order to qualify for the treatment of the above conditions with Adcirca: patients should not have concomitant conditions of low blood pressure, myocardial infarction experienced in the recent months or be particularly sensitive to tadalafil and other chemical substances contained in Adcirca. Another contraindications include loss of sight in one or both eyes because of of non-arteritic anterior ischemic optic neuropathy (NAION). Tadalafil and other PDE5 inhibitors are not compatible with nitrates and other drugs of PDE5 class used for ED treatment.

A pill of Adcirca is normally taken at tadalafil 40 mg strength twice daily with no regard to meal timing, subject to adjustment as seen necessary by the prescriber, especially in geriatric population and individuals with comorbidities (kidney or liver dysfunction).

Adcirca For When BPH And ED Conditions Coincide

One in ten men suffers from erectile dysfunction, and in 50% of cases it is accompanied by enlarged prostate gland hypertrophy which in its turn affects 16% of population. Both condition can be very taxing for both body and psyche, causing understandable physical disturbance and intrapersonal difficulty.

The correlation between prostate and erection troubles is well established. And not only that; when you have strong disappointment in the sexual sphere becomes easy to fall into a state of stress and depression. This does nothing but accentuating and aggravating the physiological damage. Erection problems arise as a result. And this is not a shortcut known by many people. It is important that every man is interested in the relationship between erectile dysfunction and prostate. As the prostate health problems are statistically very frequent and may occur as early as age 30, or earlier. And it is very easy that erectile dysfunction lead to a psychological demolition of the man who experiences the problem.

Read also: Truths and Myths of Most Popular ED Pills: Viagra vs. Cialis

Because of sexual disappointment that might happen with their partners, real episodes of sexual performance anxiety become an issue as well. Sexual performance anxiety, being one of the most common causes of erection problems will only get worse the bigger picture. still feeding more the erectile dysfunction, bringing the man into an endless spiral of cause-deepening effect.

Having suspected of having a prostate problem and strong suspicions that the prostate report and erection is compromised, you should immediately consult your doctor to perform specific analysis. To check which type of prostatitis is, or whether it is different matter. It will then be an andrologist or urologist to determine the appropriate pharmacological therapy.

But it must be said that the drug treatments are aimed mostly to the suppression of symptoms rather than to eliminate the real root causes of the various prostate problems. In fact very often they do not prove effective drugs. This makes that the relationship between the prostate and erection is increasingly evident and compromised. In relation to this, tadalafil found in Adcirca is a wiser choice that entails medicating the cause and curbing symptoms at the same time.

Furthermore, since the issue of drug compatibility is a constant challenge with both drug prescribers and their takers, it is often rather tricky to appoint therapy for both conditions with pharmaceutical products that do not clash or diminish each other’s effects. Easily then, Adcirca is an optimal solution that treats both conditions at one intake. Or rather, as it is the case with BPH, at two intakes daily.

We would like to remind you that appointing a drug is a task that should be performed by your doctor, be it urologist, GP, sexologist or any other professional healthcare provider whom you trust. And while at My Canadian Pharmacy www.mycanadianpharmacyrx.com you can receive qualified medical consulting, your physical presence is important for a thorough examination to take place. It is also important to introduce necessary lifestyle changes to fend off the diseases for as long as possible when the therapy is over.